Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | CASP1 | P29466 | 2/20 | 0.73 |
| ▸ | CASP7 | P55210 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718553 | 0.92 | USP2 (0.75) | ALDH1A1CASP1CASP7GAAUSP2 | |
| SCHEMBL1718872 | 0.89 | USP2 (0.67) | ALDH1A1CASP1CASP7GAAUSP2 | |
| SCHEMBL14013224 | 0.87 | ALDH1A1 (0.60) | ALDH1A1CASP1CASP7GAAHPGD | |
| SCHEMBL4206529 | 0.86 | ALDH1A1 (0.83) | ALDH1A1CASP1CASP7GAAUSP2 | |
| SCHEMBL4203621 | 0.85 | ALDH1A1 (0.70) | ALDH1A1CASP1CASP7GAAHPGD | |
| SCHEMBL4206649 | 0.84 | ALDH1A1 (0.79) | ALDH1A1CASP1CASP7GAAUSP2 | |
| SCHEMBL1718817 | 0.84 | HPGD (0.75) | ALDH1A1CASP1CASP7HPGDCYP1A2 | |
| SCHEMBL4203875 | 0.82 | ALDH1A1 (0.71) | ALDH1A1CASP1CASP7GAAUSP2 | |
| SCHEMBL1717999 | 0.82 | ALDH1A1 (0.77) | ALDH1A1CASP1CASP7GAAUSP2 | |
| SCHEMBL1719729 | 0.82 | USP2 (0.56) | ALDH1A1CASP1CASP7GAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |