Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190033 | 0.89 | TLR7 (0.48) | TLR7IL6 | |
| SCHEMBL15432959 | 0.86 | TLR7 (0.47) | TLR7IL6 | |
| SCHEMBL4134349 | 0.86 | TLR7 (0.54) | TLR7IL6 | |
| SCHEMBL15432951 | 0.86 | TLR7 (0.40) | TLR7 | |
| SCHEMBL4135343 | 0.86 | TLR7 (0.53) | TLR7IL6 | |
| SCHEMBL13849545 | 0.85 | TLR7 (0.52) | TLR7IL6 | |
| SCHEMBL17190034 | 0.85 | TLR7 (0.47) | TLR7IL6 | |
| SCHEMBL21076667 | 0.81 | TLR7 (0.70) | TLR7 | |
| SCHEMBL4468323 | 0.80 | TLR7 (0.57) | TLR7 | |
| SCHEMBL17190031 | 0.79 | TLR7 (0.50) | TLR7IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150299221-A1 | MACROCYCLIC PURINES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299221-A1 | MACROCYCLIC PURINES FOR THE TREATMENT OF VIRAL INFECTIONS | PNP, HPRT1, UMPS | TLR7 316/4885IL6 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.