Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12693970 | 0.80 | CYP3A4 (0.30) | TDP1CYP3A4 | |
| SCHEMBL322574 | 0.78 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL1646006 | 0.78 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL14617914 | 0.74 | CYP3A4 (0.41) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL2574194 | 0.74 | MEN1 (0.42) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL14271678 | 0.72 | TAAR1 (0.39) | TDP1CYP3A4ALDH1A1TSHRKMT2A | |
| SCHEMBL28635021 | 0.71 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL16841448 | 0.70 | TDP1 (0.38) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL11727815 | 0.70 | TDP1 (0.38) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL32679515 | 0.69 | CYP3A4 (0.47) | TDP1CYP3A4ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9731282-B2 | Ligand compound, organic chromium compound, catalyst system for ethylene oligomerization, preparation method thereof, and ethylene oligomerization method using the same | LG CHEM, LTD. (KR) | 2017-08-15 | — | — | US | disclosed |
| US-9731282-B2 | Ligand compound, organic chromium compound, catalyst system for ethylene oligomerization, preparation method thereof, and ethylene oligomerization method using the same | LG CHEM, LTD. (KR) | 2017-08-15 | — | — | US | disclosed |
| US-20150298110-A1 | LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND, CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION, PREPARATION METHOD THEREOF, AND ETHYLENE OLIGOMERIZATION METHOD USING THE SAME | LG CHEM, LTD. (KR) | 2015-10-22 | — | — | US | disclosed |
| US-20150298110-A1 | LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND, CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION, PREPARATION METHOD THEREOF, AND ETHYLENE OLIGOMERIZATION METHOD USING THE SAME | LG CHEM, LTD. (KR) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150298110-A1 | LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND, CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION, PREPARATION METHOD THEREOF, AND ETHYLENE OLIGOMERIZATION METHOD USING THE SAME | OXER1, ORC3, OR51E2 | TDP1 2486/4885CYP3A4 632/4885ESR1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.