Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719920 | 0.87 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL1718312 | 0.86 | HPGD (0.60) | KDM4EALDH1A1SMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL1719113 | 0.84 | ALDH1A1 (0.61) | KDM4EALDH1A1SMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL1718787 | 0.82 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL1718989 | 0.81 | MAPT (0.75) | KDM4EALDH1A1SMN1; SMN2L3MBTL1HSD17B10 | |
| Benzylamine SCHEMBL1719060 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL1718629 | 0.72 | HPGD (0.68) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1718870 | 0.71 | ALDH1A1 (0.71) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1718061 | 0.70 | TP53 (0.67) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1718692 | 0.70 | HPGD (0.67) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |