Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359343 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2ATNF | |
| SCHEMBL2845041 | 0.76 | TNF (0.36) | ALDH1A1TDP1MEN1KMT2ATNF | |
| SCHEMBL16268047 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TDP1MEN1KMT2ATNF | |
| SCHEMBL488952 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TDP1MEN1KMT2ATNF | |
| SCHEMBL17190700 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL31387760 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL953875 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL1359122 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL7550008 | 0.71 | CA12 (0.38) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL7550001 | 0.71 | CA12 (0.38) | ALDH1A1TDP1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150299170-A1 | FLUORO-DERIVATIVES OF PYRAZOLE-SUBSTITUTED AMINO-HETEROARYL COMPOUNDS | CONCERT PHARMACEUTICALS INC (US) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299170-A1 | FLUORO-DERIVATIVES OF PYRAZOLE-SUBSTITUTED AMINO-HETEROARYL COMPOUNDS | ALK, ABL1, BRAF | ALDH1A1 395/4885TDP1 1325/4885MEN1 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.