Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17192989 | 1.00 | P2RY2 (0.33) | P2RY2P2RY4NT5E | |
| SCHEMBL17192971 | 1.00 | P2RY2 (0.33) | P2RY2P2RY4NT5E | |
| SCHEMBL17191719 | 1.00 | P2RY2 (0.33) | P2RY2P2RY4NT5E | |
| SCHEMBL23225579 | 0.91 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL15739601 | 0.91 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL19250773 | 0.91 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL15739535 | 0.91 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL17192983 | 0.91 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL17192969 | 0.91 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL17191720 | 0.91 | P2RY2 (0.32) | P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732111-B2 | 2′-alkynyl substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732111-B2 | 2′-alkynyl substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150299243-A1 | 2'-ALKYNYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299243-A1 | 2'-ALKYNYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | PNP, SLC29A2, HAVCR2 | P2RY2 228/4885P2RY4 257/4885NT5E 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.