Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23225579 | 1.00 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL15739601 | 1.00 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL17192983 | 1.00 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL15739535 | 1.00 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL17192969 | 1.00 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL17191719 | 0.91 | P2RY2 (0.33) | P2RY2P2RY4 | |
| SCHEMBL17191734 | 0.91 | P2RY2 (0.33) | P2RY2P2RY4 | |
| SCHEMBL17192989 | 0.91 | P2RY2 (0.33) | P2RY2P2RY4 | |
| SCHEMBL17192971 | 0.91 | P2RY2 (0.33) | P2RY2P2RY4 | |
| SCHEMBL17191720 | 0.89 | P2RY2 (0.32) | P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732111-B2 | 2′-alkynyl substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |