Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | AOC1 | P19801 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283960 | 0.88 | GAA (0.52) | LOXL2HRH3GAAF10CYP3A4 | |
| SCHEMBL27813672 | 0.84 | PRSS1 (0.39) | LOXL2ABATGAAF10CYP3A4 | |
| SCHEMBL10061520 | 0.84 | TAAR1 (0.41) | LOXL2GAACYP3A4KDM4EMEN1 | |
| SCHEMBL27892650 | 0.84 | LOXL2 (0.41) | LOXL2HRH3ABATROCK1GAA | |
| SCHEMBL15699808 | 0.84 | LOXL2 (0.41) | LOXL2HRH3ABATROCK1GAA | |
| SCHEMBL2037286 | 0.84 | CSNK2A1 (0.46) | LOXL2HRH3ROCK1GAACYP3A4 | |
| SCHEMBL27656591 | 0.84 | CYP3A4 (0.39) | LOXL2HRH3ABATGAAF10 | |
| SCHEMBL27833864 | 0.84 | LOXL2 (0.36) | LOXL2HRH3ABATGAAF10 | |
| SCHEMBL28875537 | 0.82 | SKP2 (0.44) | — | |
| SCHEMBL22106784 | 0.81 | LOXL2 (0.38) | LOXL2HRH3ABATROCK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015161142-A1 | QUINOXALINE COMPOUNDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-10-22 | — | — | WO | disclosed |