Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12887815 | 0.84 | KCNH2 (0.30) | KCNH2 | |
| SCHEMBL10129937 | 0.83 | LRRK2 (0.35) | LRRK2 | |
| SCHEMBL28156988 | 0.82 | — | — | |
| SCHEMBL22275230 | 0.82 | — | — | |
| SCHEMBL23736428 | 0.78 | LRRK2 (0.33) | LRRK2 | |
| SCHEMBL13734950 | 0.72 | CYP11B1 (0.30) | — | |
| SCHEMBL17072614 | 0.72 | — | — | |
| SCHEMBL15100969 | 0.72 | BAZ2B (0.37) | — | |
| SCHEMBL12203385 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL22275476 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015158427-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2015-10-22 | — | — | WO | disclosed |