Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 15/20 | 0.51 |
| ▸ | TTK | P33981 | 4/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172059 | 0.76 | PIK3CG (0.51) | PIK3CGTTKPIK3CDPIK3CATDP2 | |
| SCHEMBL798967 | 0.75 | PIK3CG (0.51) | PIK3CGTTKPIK3CDPIK3CATDP2 | |
| SCHEMBL3098795 | 0.70 | PIK3CG (0.80) | PIK3CGTTKPIK3CDPIK3CATDP2 | |
| SCHEMBL3090168 | 0.70 | PIK3CG (0.75) | PIK3CGTTKPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3094019 | 0.69 | PIK3CG (0.78) | PIK3CGTTKPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3101636 | 0.69 | PIK3CG (1.00) | PIK3CGTTKPIK3CDPIK3CATDP2 | |
| SCHEMBL3091846 | 0.68 | PIK3CG (0.80) | PIK3CGTTKPIK3CDPIK3CAPIK3CB | |
| SCHEMBL799223 | 0.68 | PIK3CG (0.56) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL13154325 | 0.67 | PIK3CG (0.76) | PIK3CGTTKPIK3CDPIK3CATDP2 | |
| SCHEMBL3094738 | 0.66 | PIK3CG (0.74) | PIK3CGPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426135-A1 | UREA DERIVATIVE HAVING PI3K INHIBITORY ACTIVITY | Shionogi&Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |