⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31010424 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1935427 | 0.97 | MAPK1 (0.95) | — | |
| Hydrochloric Acid SCHEMBL28232771 | 0.97 | MAPK1 (0.95) | — | |
| Tetrahydrofuran SCHEMBL27800780 | 0.84 | MAPK1 (0.70) | — | |
| SCHEMBL2548188 | 0.75 | MAPK1 (0.56) | — | |
| SCHEMBL22970755 | 0.69 | MAPK1 (0.50) | — | |
| SCHEMBL329638 | 0.69 | — | — | |
| SCHEMBL31434925 | 0.67 | MAPK1 (0.50) | — | |
| SCHEMBL26038410 | 0.67 | MAPK1 (0.50) | — | |
| SCHEMBL18207739 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648763-A2 | COMPOUNDS FOR FGFRS INHIBITORS | Cogent Biosciences, Inc. (US) | 2025-11-19 | — | — | EP | claimed |
| WO-2025082069-A1 | COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN | 中国海洋大学 | 2025-04-24 | — | — | WO | claimed |
| US-20240270741-A1 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. | 2024-08-15 | — | — | US | claimed |
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | claimed |
| CN-112218631-B | Heterocyclic inhibitors of ATR kinase | 德州大学系统董事会 | 2023-12-22 | — | — | CN | claimed |
| EP-3765008-B1 | HETEROCYCLIC INHIBITORS OF ATR KINASE | UNIV TEXAS (US) | 2023-06-07 | — | — | EP | claimed |
| US-20220127276-A1 | PYRAZINE DERIVATIVE AND APPLICATION THEREOF IN INHIBITING SHP2 | SUZHOU GENHOUSE PHARMACEUTICAL CO., LTD (CN) | 2022-04-28 | — | — | US | claimed |
| CN-114195799-A | Pyrazine derivative and application thereof in inhibition of SHP2 | 勤浩医药（苏州）有限公司 | 2022-03-18 | — | — | CN | claimed |
| EP-3936502-A1 | PYRAZINE DERIVATIVE AND APPLICATION THEREOF IN INHIBITING SHP2 | Suzhou Genhouse Pharmaceutical Co., Ltd. (CN) | 2022-01-12 | — | — | EP | claimed |
| CN-113474338-A | Pyrazine derivative and application thereof in inhibition of SHP2 | 勤浩医药（苏州）有限公司 | 2021-10-01 | — | — | CN | claimed |
| US-6528227-B2 | Radiation-sensitive black-and-white silver halide photographic material in contact with screen sheets designed to emit electrons when exposed to X-rays with an energy greater than or equal to 10 kVp; radiology | AGFA-GEVAERT (BE) | 2003-03-04 | — | — | US | claimed |
| US-20020076640-A1 | Film/screen system and image-forming system for use in direct X-ray applications | AGFA-GEVAERT (BE) | 2002-06-20 | — | — | US | claimed |
| EP-1195641-A1 | Film/Screen system and image-forming system for use in direct X-ray applications | Agfa-Gevaert (BE) | 2002-04-10 | — | — | EP | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| EP-0534323-B1 | Process for the preparation of high chloride tabular grain emulsions (II) | EASTMAN KODAK CO (US) | 1997-05-14 | — | — | EP | claimed |
| US-5391468-A | With emulsion layer containing blend of spectrally sensitized tabular iodohalide grains and second, slower, fine grain population of higher solubility silver salt content having second dye adsorbed to surface | EASTMAN KODAK COMPANY (US) | 1995-02-21 | — | — | US | claimed |
| US-5389509-A | Surface treatment of grains with an organonitrogen compound | EASTMAN KODAK COMPANY (US) | 1995-02-14 | — | — | US | claimed |
| EP-0534323-A1 | Process for the preparation of high chloride tabular grain emulsions (II) | EASTMAN KODAK COMPANY (US) | 1993-03-31 | — | — | EP | claimed |
| US-5178997-A | A fused N-heterocyclic compound as a grain growth modifier; materials handling | EASTMAN KODAK COMPANY (US) | 1993-01-12 | — | — | US | claimed |