SCHEMBL17198680

SCHEMBL17198680

Cc1ncc(SC(F)(F)F)s1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12206091 0.73
SCHEMBL25647766 0.71
SCHEMBL21133103 0.68
SCHEMBL12058917 0.67 HCAR2 (0.39) HCAR2
SCHEMBL17198660 0.67 GLP1R (0.43) SMN1; SMN2
SCHEMBL26859996 0.65 HCAR2 (0.34) HCAR2
SCHEMBL17198651 0.65 KDM4E (0.32) SMN1; SMN2
SCHEMBL21209899 0.65 HCAR2 (0.38) HCAR2
SCHEMBL2669083 0.64 HRH1 (0.37) HCAR2
SCHEMBL2669095 0.64 CA2 (0.38) HCAR2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015158605-A1 HETARYL SUBSTITUTED MALONONITRILE COMPOUNDS BASF SE (DE) 2015-10-22 WO disclosed