SCHEMBL17198782

SCHEMBL17198782

CCCCOC(=O)[C@@H](C)N[P@@]1(=O)OC[C@H]2[C@@H](O)[C@H](n3ccc(=O)[nH]c3=O)O[C@@H]2CO1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.39
▸ SLC28A2 O43868 1/20 0.39
▸ SLC29A1 Q99808 1/20 0.39
▸ SLC28A3 Q9HAS3 1/20 0.39
▸ STING1 Q86WV6 1/20 0.38
▸ P2RY2 P41231 5/20 0.38
▸ P2RY1 P47900 1/20 0.38
▸ P2RY6 Q15077 4/20 0.38
▸ P2RY4 P51582 2/20 0.38
▸ ENTPD2 Q9Y5L3 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17198774 1.00 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3STING1
SCHEMBL17198783 1.00 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3STING1
SCHEMBL17198784 1.00 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3STING1
SCHEMBL17198781 1.00 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3STING1
SCHEMBL17198411 1.00 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3STING1
SCHEMBL17198789 1.00 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3STING1
SCHEMBL17198252 0.88 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17198775 0.88 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17198251 0.88 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17198768 0.88 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170044205-A1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES NUCLEOTIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS, INC. 2017-02-16 — — US disclosed
US-20170044205-A1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES NUCLEOTIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS, INC. 2017-02-16 — — US disclosed
WO-2015161137-A1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS, INC. (US) 2015-10-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044205-A1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES NUCLEOTIDES FOR THE TREATMENT OF HCV RB1, NSUN2, METTL3 SLC28A1 82/4885SLC28A2 32/4885SLC29A1 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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