Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17186325 | 0.86 | KDM4E (0.60) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3510455 | 0.86 | KDM4E (0.79) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7846212 | 0.85 | KDM4E (0.60) | KDM4EPOLBSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17186457 | 0.85 | KDM4E (0.59) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL18605769 | 0.84 | KDM4E (0.77) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11318575 | 0.80 | KDM4E (0.67) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4915214 | 0.80 | SMN1; SMN2 (0.73) | KDM4ESMN1; SMN2NPC1RAB9AROCK2 | |
| SCHEMBL2730689 | 0.78 | SMN1; SMN2 (0.85) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3430425 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL171893 | 0.77 | KDM4E (0.62) | KDM4ESMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015160220-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | HANALL BIOPHARMA CO., LTD. (KR) | 2015-10-22 | — | — | WO | disclosed |