Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | MAX | P61244 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718002 | 0.90 | KMT2A (0.65) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1719015 | 0.90 | KMT2A (0.58) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1719448 | 0.89 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1719596 | 0.89 | KMT2A (0.56) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1718447 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1718710 | 0.89 | ALDH1A1 (0.65) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1719290 | 0.87 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1718748 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1718417 | 0.86 | RXFP1 (0.66) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1719214 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |