Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593916 | 0.94 | FAAH (1.00) | FAAH | |
| SCHEMBL3609268 | 0.91 | FAAH (1.00) | FAAH | |
| SCHEMBL3600266 | 0.90 | FAAH (1.00) | FAAH | |
| SCHEMBL3588127 | 0.90 | FAAH (1.00) | FAAH | |
| SCHEMBL3604133 | 0.90 | FAAH (1.00) | FAAH | |
| SCHEMBL3596266 | 0.88 | FAAH (1.00) | FAAH | |
| SCHEMBL3597975 | 0.87 | FAAH (1.00) | FAAH | |
| SCHEMBL3584013 | 0.87 | FAAH (1.00) | FAAH | |
| SCHEMBL3606516 | 0.86 | FAAH (1.00) | FAAH | |
| SCHEMBL3594633 | 0.86 | FAAH (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937341-A1 | 4-(BENZYL)-PIPERAZINE-1-CARBOXYLIC ACID PHENYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE (FAAH) FOR THE TREATMENT OF ANXIETY, PAIN AND OTHER CONDITIONS | Janssen Pharmaceutica N.V. (BE) | 2015-10-28 | — | — | EP | disclosed |