Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17200021 | 1.00 | HCAR2 (0.56) | HCAR2CYP1A2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3513899 | 0.78 | HCAR2 (0.69) | HCAR2CYP1A2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6832853 | 0.78 | HCAR2 (0.69) | HCAR2CYP1A2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5987501 | 0.77 | CHRNA7 (0.45) | HCAR2 | |
| SCHEMBL6153171 | 0.77 | CHRNA7 (0.45) | HCAR2 | |
| SCHEMBL5987504 | 0.77 | CHRNA7 (0.45) | HCAR2 | |
| SCHEMBL6153169 | 0.77 | CHRNA7 (0.45) | HCAR2 | |
| SCHEMBL7040434 | 0.77 | DRD2 (0.63) | CYP1A2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL21593634 | 0.77 | DRD2 (0.63) | CYP1A2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7040433 | 0.77 | DRD2 (0.63) | CYP1A2RAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635567-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2015-10-28 | — | — | EP | claimed |