Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296198 | 0.76 | TSHR (0.50) | POLBLMNAHTTMAPTKMT2A | |
| SCHEMBL11900604 | 0.74 | LMNA (0.64) | POLBLMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL3500290 | 0.72 | LMNA (0.61) | POLBLMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL29345120 | 0.72 | POLB (0.58) | POLBLMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11810697 | 0.71 | LMNA (1.00) | POLBLMNASMN1; SMN2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL31046342 | 0.70 | POLB (0.59) | POLBLMNASMN1; SMN2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL31046243 | 0.69 | POLB (0.55) | POLBLMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11812589 | 0.69 | LMNA (0.94) | POLBLMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1309697 | 0.69 | PIK3CA (0.52) | POLBLMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11895982 | 0.69 | GAA (0.44) | POLBSMN1; SMN2HTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473486-B2 | PYRIMIDINES AS HEPCIDINE ANTAGONISTS | VIFOR INT AG (CH) | 2021-09-22 | — | — | EP | disclosed |
| EP-2473486-B1 | PYRIMIDINES AS HEPCIDINE ANTAGONISTS | VIFOR INT AG (CH) | 2015-10-28 | — | — | EP | disclosed |