Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13446183 | 0.69 | — | — | |
| SCHEMBL15338716 | 0.67 | — | — | |
| SCHEMBL9721225 | 0.67 | — | — | |
| SCHEMBL1000250 | 0.67 | TET2 (0.50) | TET2 | |
| SCHEMBL1000252 | 0.67 | TET2 (0.50) | TET2 | |
| SCHEMBL6437940 | 0.65 | POLB (0.35) | TET2 | |
| SCHEMBL14159093 | 0.64 | — | — | |
| SCHEMBL28858564 | 0.63 | THRB (0.41) | — | |
| SCHEMBL11602159 | 0.62 | — | — | |
| SCHEMBL27469285 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426109-A1 | NOVEL KINASE INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-03-07 | — | — | EP | disclosed |