Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 19/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178506 | 0.73 | PI4KB (0.42) | PI4KBPI4KAPI4K2BPI4K2AKCNH2 | |
| SCHEMBL14670870 | 0.73 | PI4KB (0.42) | PI4KBPI4KAPI4K2BPI4K2AKCNH2 | |
| SCHEMBL10244405 | 0.70 | NTRK1 (0.42) | GLP1R | |
| SCHEMBL14667014 | 0.69 | PI4KB (0.39) | PI4KBPI4KAPI4K2BPI4K2AKCNH2 | |
| SCHEMBL14665404 | 0.69 | PI4KB (0.39) | PI4KBPI4KAPI4K2BPI4K2AKCNH2 | |
| SCHEMBL14669274 | 0.69 | PI4KB (0.39) | PI4KBPI4KAPI4K2BPI4K2AKCNH2 | |
| SCHEMBL655136 | 0.65 | IKBKB (0.47) | — | |
| SCHEMBL11061973 | 0.62 | GLP1R (0.44) | GLP1R | |
| SCHEMBL31065829 | 0.62 | PI4KB (0.52) | PI4KBPI4KAPI4K2BPI4K2A | |
| SCHEMBL21899246 | 0.58 | GLP1R (0.35) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103130-A2 | NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2010-09-16 | — | — | WO | disclosed |