SCHEMBL10244405

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11202541	0.73	ADORA2A (0.47)	NTRK1NTRK2CLK4CHEK1AURKA
	SCHEMBL10245410	0.73	DYRK1A (0.49)	NTRK1NTRK2CLK4CHEK1AURKA
	SCHEMBL2369026	0.72	ADORA2A (0.58)	NTRK1NTRK2CLK4CHEK1AURKA
	SCHEMBL30373476	0.72	ADORA2A (0.58)	NTRK1NTRK2CLK4CHEK1AURKA
	SCHEMBL1720111	0.70	PI4KB (0.37)	GLP1R
	SCHEMBL4737163	0.69	NTRK1 (0.44)	NTRK1NTRK2CLK4CHEK1AURKA
	SCHEMBL10244398	0.69	KMT2A (0.45)	NTRK1NTRK2CLK4CHEK1AURKA
	SCHEMBL5336326	0.67	PIP4K2A (0.37)	NTRK1NTRK2CLK4CHEK1AURKA
	SCHEMBL29994750	0.66	NTRK1 (0.41)	NTRK1NTRK2CLK4CHEK1AURKA
	SCHEMBL4098622	0.64	ADORA2A (0.57)	CLK4CSNK1A1ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.