Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17201431 | 0.84 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17201432 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17201425 | 0.84 | NR4A2 (0.44) | MAPTNR4A2ALOX5ALOX5APMAOB | |
| SCHEMBL15774381 | 0.84 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17201439 | 0.83 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17201440 | 0.83 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17201429 | 0.83 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17201422 | 0.82 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL15774561 | 0.81 | MAOB (0.54) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17201417 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333764-A | Substituted azole derivatives, pharmaceutical composition containing the derivatives, and method for treating parkinson's disease using the same | SK HOLDINGS CO LTD | 2012-01-25 | — | — | CN | claimed |
| US-9296711-B2 | Substituted isoxazole amide compounds as inhibitors of stearoyl-CoA desaturase 1 (SCD1) | HOFFMAN-LA ROCHE INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150307463-A1 | SUBSTITUTED ISOXAZOLE AMIDE COMPOUNDS AS INHIBITORS OF STEAROYL-COA DESATURASE 1 (SCD1) | HOFFMANN-LA ROCHE INC. | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307463-A1 | SUBSTITUTED ISOXAZOLE AMIDE COMPOUNDS AS INHIBITORS OF STEAROYL-COA DESATURASE 1 (SCD1) | SCD, SCD5, CPT1A | CYP1A2 368/4885CYP2D6 747/4885CYP2C19 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.