Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746944 | 1.00 | TP53 (0.41) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL8036456 | 1.00 | TP53 (0.41) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL24827776 | 0.81 | — | — | |
| SCHEMBL791803 | 0.81 | — | — | |
| SCHEMBL275810 | 0.81 | — | — | |
| SCHEMBL5371229 | 0.81 | — | — | |
| SCHEMBL4572067 | 0.81 | — | — | |
| SCHEMBL9880195 | 0.81 | — | — | |
| SCHEMBL4448763 | 0.81 | — | — | |
| SCHEMBL10559661 | 0.81 | CHRM1 (0.46) | TP53ALDH1A1ACE2TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-05 | — | — | US | disclosed |
| US-20190345462-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | UNITED STATES DEPARTMENT OF ENERGY | 2019-11-14 | — | — | US | disclosed |
| US-20190345462-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | UNITED STATES DEPARTMENT OF ENERGY | 2019-11-14 | — | — | US | disclosed |
| US-10233431-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-03-19 | — | — | US | disclosed |
| US-10233431-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-03-19 | — | — | US | disclosed |
| US-20150307855-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
| US-20150307855-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
| US-20150307855-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345462-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | COASY, FASN, DHPS | TP53 4456/4885ALDH1A1 1555/4885ACE 2653/4885 |
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | COASY, FASN, DHPS | TP53 4456/4885ALDH1A1 1555/4885ACE 2653/4885 |
| US-10233431-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | COASY, FASN, DHPS | TP53 4456/4885ALDH1A1 1555/4885ACE 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.