⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006483 | 0.85 | CYP3A4 (0.43) | — | |
| SCHEMBL3007784 | 0.74 | — | — | |
| SCHEMBL29028258 | 0.74 | CYP3A4 (0.41) | — | |
| SCHEMBL3006863 | 0.70 | — | — | |
| Carbon Monoxide SCHEMBL1982955 | 0.70 | — | — | |
| SCHEMBL114543 | 0.70 | CYP3A4 (0.50) | — | |
| SCHEMBL3007015 | 0.68 | CYP3A4 (0.43) | — | |
| SCHEMBL5388290 | 0.67 | CYP3A4 (0.47) | — | |
| SCHEMBL8539745 | 0.67 | CYP3A4 (0.47) | — | |
| SCHEMBL9661126 | 0.67 | CYP3A4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057127-B1 | HYDANTOIN DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | SCHERING CORP (US) | 2012-01-11 | — | — | EP | disclosed |
| US-7998961-B2 | For treating conditions associated with UDP-3-O (R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) | SCHERING CORPORATION (US) | 2011-08-16 | — | — | US | disclosed |
| EP-2057127-A1 | HYDANTOIN DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | SCHERING CORPORATION (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008027466-A1 | HYDANTOIN DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | SCHERING CORPORATION (US) | 2008-03-06 | — | — | WO | disclosed |