Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15569111 | 0.88 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6924337 | 0.85 | SLC6A4 (0.59) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL17201766 | 0.84 | KDM4E (0.58) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL17201769 | 0.83 | KDM4E (0.57) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL17201771 | 0.81 | KDM4E (0.47) | SMN1; SMN2L3MBTL1TDP1KDM4EALOX5AP | |
| SCHEMBL812065 | 0.79 | KDM4E (0.59) | RAB9AL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL15569110 | 0.78 | KDM4E (0.53) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL29419188 | 0.77 | SMN1; SMN2 (1.00) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL15569131 | 0.74 | TDP1 (0.45) | SMN1; SMN2L3MBTL1SLC6A4SLC6A3TDP1 | |
| SCHEMBL19895143 | 0.74 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409881-B2 | Herbicidally active 6′-phenyl-2,2′-bipyridine-3-carboxylic acid derivatives | BAYER CROPSCIENCE AG (AG) | 2016-08-09 | — | — | US | disclosed |
| US-20150307470-A1 | HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307470-A1 | HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES | CBR3, DDT, CBR1 | NPC1 4588/4885RAB9A 2420/4885SMN1; SMN2 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.