Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17201766 | 0.90 | KDM4E (0.58) | KDM4ETDP1KMOSMN1; SMN2DHODH | |
| SCHEMBL17201769 | 0.88 | KDM4E (0.57) | KDM4ETDP1KMOSMN1; SMN2DHODH | |
| SCHEMBL15567980 | 0.82 | KDM4E (0.54) | KDM4ETDP1KMOSMN1; SMN2DHODH | |
| SCHEMBL15569130 | 0.81 | KDM4E (0.62) | KDM4ETDP1SMN1; SMN2DHODHRAB9A | |
| SCHEMBL17201767 | 0.81 | KDM4E (0.53) | KDM4ETDP1KMOSMN1; SMN2DHODH | |
| Potassium SCHEMBL17201770 | 0.81 | KDM4E (0.53) | KDM4ETDP1KMOSMN1; SMN2DHODH | |
| SCHEMBL6924541 | 0.79 | KDM4E (0.67) | KDM4ETDP1KMOTRPV1SMN1; SMN2 | |
| SCHEMBL31676801 | 0.79 | KDM4E (0.67) | KDM4ETDP1KMOTRPV1SMN1; SMN2 | |
| SCHEMBL15467864 | 0.78 | KDM4E (0.66) | KDM4ETDP1SMN1; SMN2DHODHMEN1 | |
| SCHEMBL17201765 | 0.78 | NPC1 (0.62) | KDM4ETDP1KMOTRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882732-B1 | HERBICIDALLY ACTIVE DERIVATIVES OF 6'-PHENYL-2,2'-BIPYRIDIN-3-CARBOXYLIC ACID | BAYER CROPSCIENCE AG (DE) | 2017-04-12 | — | — | EP | disclosed |
| EP-2882732-A1 | HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014023670-A1 | HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-02-13 | — | — | WO | disclosed |