Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724173 | 0.90 | APP (0.54) | MAOBARAPPNPC1POLB | |
| SCHEMBL30655811 | 0.85 | MAOB (0.47) | MAOBARAPPNPC1POLB | |
| SCHEMBL310367 | 0.85 | MAOB (0.60) | MAOBAPPNPC1POLBRAB9A | |
| SCHEMBL9228037 | 0.84 | MAOB (0.57) | MAOBAR | |
| SCHEMBL30724171 | 0.82 | AR (0.53) | MAOBARAPPNPC1POLB | |
| SCHEMBL7240384 | 0.81 | MAOB (0.53) | MAOBAPPNPC1POLBRAB9A | |
| SCHEMBL18164596 | 0.80 | MAOB (0.70) | MAOBAPPNPC1POLBRAB9A | |
| SCHEMBL2554931 | 0.80 | MAOB (0.45) | MAOBARAPPNPC1POLB | |
| SCHEMBL18164564 | 0.79 | MAOB (0.59) | MAOBAPPNPC1RAB9A | |
| SCHEMBL5783571 | 0.79 | NOTUM (0.51) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162538-A1 | HETEROCYCLIC COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS FOR THE TREATMENT OF HYPERPARATHYROIDISM, CHRONIC RENAL FAILURE AND CHRONIC KIDNEY DISEASE | LUPIN LIMITED (IN) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162538-A1 | HETEROCYCLIC COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS FOR THE TREATMENT OF HYPERPARATHYROIDISM, CHRONIC RENAL FAILURE AND CHRONIC KIDNEY DISEASE | LUPIN LIMITED (IN) | 2015-10-29 | — | — | WO | disclosed |