Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | APP | P05067 | 7/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310367 | 0.89 | MAOB (0.60) | MAOBAPPFFAR1NPC1RAB9A | |
| SCHEMBL14895605 | 0.89 | MAOB (0.60) | MAOBAPPFFAR1NPC1RAB9A | |
| SCHEMBL7803831 | 0.84 | TUBB1 (0.47) | MAOBFFAR1SMN1; SMN2 | |
| SCHEMBL2226602 | 0.82 | MAOB (0.62) | MAOBFFAR1RAB9ASMN1; SMN2 | |
| SCHEMBL7240044 | 0.81 | MAOB (0.53) | MAOBAPPFFAR1NPC1RAB9A | |
| SCHEMBL3930569 | 0.81 | APP (0.63) | MAOBAPPNPC1RAB9APOLB | |
| SCHEMBL17205237 | 0.81 | MAOB (0.49) | MAOBAPPNPC1RAB9APOLB | |
| SCHEMBL1195442 | 0.81 | MAOB (0.49) | MAOBAPPFFAR1NPC1RAB9A | |
| SCHEMBL28413184 | 0.80 | RAB9A (0.54) | MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL309260 | 0.79 | MAOB (0.50) | MAOBAPPFFAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552018-B1 | As antitumor agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-6169086-B1 | AN ANTITUMOR AGENT FOR TREATING TUMOR RESISTANT TO 5-FLUOROURACIL TYPE DRUGS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-1022270-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |