Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 3/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Banoxantrone SCHEMBL17207287 | 0.94 | NQO1 (0.61) | NQO1CYP19A1MEN1KMT2ABLM | |
| SCHEMBL17207286 | 0.94 | NQO1 (0.61) | NQO1CYP19A1MEN1KMT2ABLM | |
| Banoxantrone SCHEMBL29378863 | 0.87 | NQO1 (0.72) | NQO1CYP19A1MEN1KMT2ABLM | |
| Banoxantrone SCHEMBL3676563 | 0.87 | NQO1 (0.72) | NQO1CYP19A1MEN1KMT2ABLM | |
| Banoxantrone SCHEMBL30324147 | 0.86 | NQO1 (0.70) | NQO1CYP19A1MEN1KMT2ABLM | |
| SCHEMBL14876631 | 0.84 | CYP19A1 (0.62) | NQO1CYP19A1MEN1KMT2ABLM | |
| SCHEMBL13331702 | 0.82 | NQO1 (0.66) | NQO1CYP19A1MEN1KMT2ABLM | |
| SCHEMBL14369957 | 0.80 | NQO1 (0.64) | NQO1CYP19A1MEN1KMT2ABLM | |
| SCHEMBL14369959 | 0.79 | NQO1 (0.79) | NQO1CYP19A1MEN1KMT2ABLM | |
| SCHEMBL9364140 | 0.78 | MEN1 (0.76) | NQO1CYP19A1MEN1KMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307441-A1 | NEW COMPOUNDS AND USES THEREOF | BIOSTATUS LIMITED (GB) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307441-A1 | NEW COMPOUNDS AND USES THEREOF | HIF1AN, HIF1A, EGLN2 | NQO1 27/4885CYP19A1 430/4885MEN1 2915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.