Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.76 |
| ▸ | BLM | P54132 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | NSD2 | O96028 | 3/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | RECQL | P46063 | 2/20 | 0.76 |
| ▸ | TOP2A | P11388 | 2/20 | 0.76 |
| ▸ | MTOR | P42345 | 2/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.76 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.76 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.76 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.76 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331702 | 0.92 | NQO1 (0.66) | MEN1KMT2ALMNAMAPK1TDP1 | |
| Banoxantrone SCHEMBL3676563 | 0.90 | NQO1 (0.72) | MEN1KMT2ALMNAMAPK1TDP1 | |
| Banoxantrone SCHEMBL29378863 | 0.90 | NQO1 (0.72) | MEN1KMT2ALMNAMAPK1TDP1 | |
| Banoxantrone SCHEMBL30324147 | 0.88 | NQO1 (0.70) | MEN1KMT2ALMNAMAPK1TDP1 | |
| SCHEMBL9367584 | 0.88 | MEN1 (0.72) | MEN1KMT2ALMNAMAPK1TDP1 | |
| SCHEMBL11036806 | 0.87 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1TDP1 | |
| SCHEMBL11391594 | 0.87 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1TDP1 | |
| SCHEMBL11041207 | 0.87 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1TDP1 | |
| Mitoxantrone SCHEMBL20214110 | 0.87 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1TDP1 | |
| SCHEMBL11517949 | 0.87 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450021-B1 | ANTI-CANCER COMPOUNDS | BRITISH TECH GROUP (GB) | 1994-02-02 | — | — | EP | claimed |
| EP-0450021-B1 | ANTI-CANCER COMPOUNDS | BRITISH TECH GROUP (GB) | 1994-02-02 | — | — | EP | disclosed |