Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.62 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.48 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387351 | 0.88 | GPR119 (0.59) | GPR119 | |
| SCHEMBL456819 | 0.86 | GPR119 (0.67) | GPR119FAAH | |
| SCHEMBL2460337 | 0.84 | GPR119 (0.65) | GPR119FAAH | |
| SCHEMBL1721753 | 0.84 | GPR119 (0.54) | GPR119FAAH | |
| SCHEMBL5208507 | 0.82 | TEAD1 (0.57) | GPR119TEAD1TEAD3 | |
| SCHEMBL11956947 | 0.82 | GPR119 (0.56) | GPR119FAAHTEAD1TEAD3HRH2 | |
| SCHEMBL13908237 | 0.82 | GPR119 (0.56) | GPR119FAAHTEAD1TEAD3 | |
| SCHEMBL11956853 | 0.82 | GPR119 (0.61) | GPR119FAAHHRH2HRH1 | |
| SCHEMBL1092432 | 0.81 | GPR119 (0.65) | GPR119 | |
| SCHEMBL1092708 | 0.81 | GPR119 (0.58) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406247-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103333-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |