SCHEMBL17208465

SCHEMBL17208465

CCCCCCCC/C=C\CCCCCCCCO[C@H]1O[C@H](COS(=O)(=O)O)[C@@H](O)C[C@H]1NC(C)=O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.45
▸ CNR1 P21554 6/20 0.43
▸ CNR2 P34972 6/20 0.43
▸ TRPV1 Q8NER1 6/20 0.43
▸ BDNF P23560 3/20 0.41
▸ PTN P21246 2/20 0.41
▸ MDK P21741 2/20 0.41
▸ VEGFA P15692 4/20 0.38
▸ BMP2 P12643 1/20 0.38
▸ CXCL12 P48061 1/20 0.38
▸ SHH Q15465 1/20 0.38
▸ SELP P16109 1/20 0.37
▸ FGF1 P05230 3/20 0.36
▸ FGF2 P09038 3/20 0.36
▸ HPSE Q9Y251 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17208462 0.86 MAPK1 (0.57) MAPK1CNR1CNR2TRPV1
SCHEMBL17208463 0.83 MAPK1 (0.64) MAPK1BDNFPTNMDKVEGFA
SCHEMBL17208461 0.83 MAPK1 (0.64) MAPK1BDNFPTNMDKVEGFA
SCHEMBL17091478 0.82 MAPK1 (0.63) MAPK1BDNFPTNMDKVEGFA
SCHEMBL17117030 0.75 SELP (0.37) CNR1CNR2TRPV1BDNFPTN
SCHEMBL17208466 0.75 SELP (0.42) MAPK1BDNFPTNMDKVEGFA
Potassium Ion SCHEMBL17091479 0.75 MAPK1 (0.63) MAPK1BDNFPTNMDKVEGFA
Potassium Ion SCHEMBL17091477 0.75 MAPK1 (0.63) MAPK1BDNFPTNMDKVEGFA
SCHEMBL17210625 0.74 MAPK1 (0.54) MAPK1BDNFPTNMDKVEGFA
SCHEMBL17208460 0.74 MAPK1 (0.43) MAPK1BDNFPTNMDKVEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150307539-A1 USE OF SULPHATED GLYCOLIPIDS AS PROMOTERS OF NEURITIC GROWTH, MYELINATION AND INHIBITING THE PROLIFERATION OF ASTROGLIA AND MICROGLIA CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2015-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150307539-A1 USE OF SULPHATED GLYCOLIPIDS AS PROMOTERS OF NEURITIC GROWTH, MYELINATION AND INHIBITING THE PROLIFERATION OF ASTROGLIA AND MICROGLIA BDNF, MAG, NTRK2 MAPK1 91/4885CNR1 645/4885CNR2 286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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