Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.68 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.68 |
| ▸ | TUBB | P07437 | 4/20 | 0.68 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.68 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.68 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.68 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.68 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.68 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.68 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.68 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.68 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208664 | 1.00 | NPC1 (0.68) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL127758 | 0.95 | NPC1 (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11990636 | 0.95 | NPC1 (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL125707 | 0.95 | NPC1 (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17208665 | 0.94 | NPC1 (0.65) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17208671 | 0.94 | NPC1 (0.65) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16117338 | 0.94 | NPC1 (0.77) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17208670 | 0.94 | NPC1 (0.77) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL126855 | 0.94 | NPC1 (0.77) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18210992 | 0.94 | NPC1 (0.69) | NPC1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307468-A1 | PROCESS FOR THE PREPARATION OF CABAZITAXEL AND ITS INTERMEDIATES | INTAS PHARMACEUTICALS LIMITED (IN) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307468-A1 | PROCESS FOR THE PREPARATION OF CABAZITAXEL AND ITS INTERMEDIATES | TET1, COIL, TET3 | NPC1 1708/4885TUBB4A 91/4885TUBB 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.