Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.69 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.69 |
| ▸ | TUBB | P07437 | 4/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.69 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.69 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.69 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.69 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208673 | 0.94 | NPC1 (0.68) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17208664 | 0.94 | NPC1 (0.68) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18211051 | 0.94 | NPC1 (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15144542 | 0.91 | NPC1 (0.63) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL127758 | 0.89 | NPC1 (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11990636 | 0.89 | NPC1 (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL125707 | 0.89 | NPC1 (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17208665 | 0.89 | NPC1 (0.65) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17208671 | 0.89 | NPC1 (0.65) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17208670 | 0.88 | NPC1 (0.77) | NPC1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487496-B2 | Process for the preparation of cabazitaxel and its intermediates | INTAS PHARMACEUTICALS LIMITED (IN) | 2016-11-08 | — | — | US | disclosed |