Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17210367 | 0.98 | KDM4E (0.43) | CNR2KDM4EPOLBUSP2ALDH1A1 | |
| SCHEMBL139049 | 0.81 | KDM4E (0.58) | KDM4EPOLBUSP2ALDH1A1TSHR | |
| SCHEMBL2951425 | 0.81 | KDM4E (0.58) | KDM4EPOLBUSP2ALDH1A1TSHR | |
| SCHEMBL1928132 | 0.81 | KDM4E (0.58) | KDM4EPOLBUSP2ALDH1A1TSHR | |
| Fluoride SCHEMBL28073285 | 0.79 | KDM4E (0.56) | KDM4EPOLBUSP2ALDH1A1TSHR | |
| SCHEMBL3339822 | 0.79 | KDM4E (0.60) | KDM4EPOLBUSP2ALDH1A1TSHR | |
| SCHEMBL18228600 | 0.79 | KDM4E (0.60) | KDM4EPOLBUSP2ALDH1A1TSHR | |
| SCHEMBL23073664 | 0.79 | ROCK1 (0.41) | CNR2KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL13606214 | 0.77 | NPC1 (0.54) | CNR2KDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL16122790 | 0.77 | CNR2 (0.65) | CNR2KDM4EPOLBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015164643-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | HYDRA BIOSCIENCES, INC. (US) | 2015-10-29 | — | — | WO | disclosed |