SCHEMBL17210447

SCHEMBL17210447

C=C(NCCN)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
HTR2A P28223 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
EPHX2 P34913 1/20 0.41
FABP5 Q01469 3/20 0.40
FABP7 O15540 2/20 0.40
CASP3 P42574 1/20 0.35
TLR2 O60603 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29447213 0.82 KMT2A (0.66) KMT2AHTR2ACA1CA2EPHX2
SCHEMBL730784 0.82 KMT2A (0.66) KMT2AHTR2ACA1CA2EPHX2
Bromide SCHEMBL2216954 0.81 KMT2A (0.64) KMT2ACA1CA2EPHX2FABP5
Hydrochloric Acid SCHEMBL966018 0.81 KMT2A (0.64) KMT2ACA1CA2EPHX2FABP5
Hydrochloric Acid SCHEMBL29599906 0.81 KMT2A (0.64) KMT2ACA1CA2EPHX2FABP5
SCHEMBL10149864 0.81 KMT2A (0.48) KMT2AHTR2ACA1CA2EPHX2
SCHEMBL15521241 0.80 KMT2A (0.51) KMT2ACA1CA2EPHX2FABP5
SCHEMBL13419384 0.80 KMT2A (0.50) KMT2ACA1CA2EPHX2FABP5
SCHEMBL21526565 0.78 KMT2A (0.60) KMT2ACA1CA2EPHX2FABP5
Phosphoric Acid SCHEMBL22468200 0.78 KMT2A (0.60) KMT2ACA1CA2EPHX2FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015164289-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2015-10-29 WO disclosed