SCHEMBL730784

SCHEMBL730784

NCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.66
EPHX2 P34913 1/20 0.53
FABP7 O15540 2/20 0.46
FABP5 Q01469 2/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CASP3 P42574 2/20 0.45
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29447213 1.00 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CA1
Bromide SCHEMBL2216954 0.99 KMT2A (0.64) KMT2AEPHX2FABP7FABP5CA1
Hydrochloric Acid SCHEMBL29599906 0.99 KMT2A (0.64) KMT2AEPHX2FABP7FABP5CA1
Hydrochloric Acid SCHEMBL966018 0.99 KMT2A (0.64) KMT2AEPHX2FABP7FABP5CA1
Phosphoric Acid SCHEMBL22468200 0.95 KMT2A (0.60) KMT2AEPHX2FABP7FABP5CA1
SCHEMBL21526565 0.95 KMT2A (0.60) KMT2AEPHX2FABP7FABP5CA1
SCHEMBL1901192 0.92 KMT2A (0.70) KMT2AEPHX2FABP7FABP5CA1
Trifluoroacetic Acid SCHEMBL5553311 0.91 KMT2A (0.60) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31135496 0.90 KMT2A (0.73) KMT2AEPHX2FABP7FABP5CA1
Bromide SCHEMBL15809739 0.90 KMT2A (0.69) KMT2AEPHX2FABP7FABP5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118304441-B Tumor-targeted fluorescent probe and preparation method and application thereof 江苏省人民医院(南京医科大学第一附属医院) 2025-03-18 CN claimed
CN-118924682-A Difunctional dendritic lipopeptide nano micelle and preparation method and application thereof 中国药科大学 2024-11-12 CN claimed
WO-2024221952-A1 NANO-DELIVERY SYSTEM OF NUCLEOTIDE DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院苏州纳米技术与纳米仿生研究所 2024-10-31 WO claimed
CN-118831053-A Nanometer delivery system of nucleotide drug and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2024-10-25 CN claimed
CN-118304441-A Tumor-targeted fluorescent probe and preparation method and application thereof 江苏省人民医院(南京医科大学第一附属医院) 2024-07-09 CN claimed
US-7226636-B2 Suspension of magnetic particles in liquid; adding a gold compound; mixing with reducing agents LOS ALAMOS NATIONAL SECURITY, LLC (US) 2007-06-05 US claimed
US-20050025969-A1 Suspension of magnetic particles in liquid; adding a gold compound; mixing with reducing agents LOS ALAMOS NATIONAL SECURITY, LLC 2005-02-03 US claimed
EP-4692105-A1 CYCLIC POLYPEPTIDE COMPOUND AND USE THEREOF Bivision Pharmaceuticals, Inc (CN) 2026-02-11 EP disclosed
US-20260007756-A1 COMPOUND AND USE THEREOF COHERENT BIOPHARMA SUZHOU LTD (CN) 2026-01-08 US disclosed
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 EP disclosed
EP-4658315-A1 POLYMER-DRUG CONJUGATES Primelink Biotherapeutics (Shenzhen) Co., Ltd. (CN) 2025-12-10 EP disclosed
US-12403199-B2 Asymmetrically branched degradable polyethylene glycol derivative NOF CORPORATION (JP) 2025-09-02 US disclosed
CN-114901315-B Fibroblast Activation Protein (FAP) -targeted imaging and treatment of cancer and other fibrotic and inflammatory diseases 普渡研究基金会 2025-04-29 CN disclosed
WO-2004037772-A1 CONVENIENT AND SCALABLE SYNTHESIS OF ETHYL N-[(2-BOC-AMINO) ETHYL] GLYCINATE AND ITS HYDROCHLORIDE SALT THE UNIVERSITY OF WESTERN ONTARIO (CA) 2004-05-06 WO disclosed
WO-2003055852-A2 MULTIFUNCTIONAL REAGENT FOR THE SYNTHESIS OF THIOL MODIFIED OLIGOMERS FRIZ BIOCHEM GMBH (DE) 2003-07-10 WO disclosed
US-6518242-B1 Derivatives of glycopeptide antibacterial agents THERAVANCE, INC. 2003-02-11 US disclosed
EP-1060189-A1 DERIVATIVES OF GLYCOPEPTIDE ANTIBACTERIAL AGENTS Advanced Medicine, Inc. (US) 2000-12-20 EP disclosed
WO-1999042476-A1 NOVEL ANTIBACTERIAL AGENTS ADVANCED MEDICINE, INC. (US) 1999-08-26 WO disclosed
EP-0705279-A4 TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES SELECTIDE CORP (US) 1999-03-24 EP disclosed
EP-0705279-A1 TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES SELECTIDE CORPORATION (US) 1996-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12403199-B2 Asymmetrically branched degradable polyethylene glycol derivative MAN2B1, MGLL, PKLR KMT2A 3557/4885EPHX2 1272/4885FABP7 2803/4885
US-20260007756-A1 COMPOUND AND USE THEREOF FOLH1, TRPV6, FOLR1 KMT2A 2977/4885EPHX2 2742/4885FABP7 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.