SCHEMBL17210588

SCHEMBL17210588

Cc1cc(NC(=O)CC(S)C(=O)O)ccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ POLB P06746 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ ATM Q13315 1/20 0.50
▸ PLEC Q15149 1/20 0.50
▸ CA9 Q16790 14/20 0.49
▸ CA1 P00915 13/20 0.49
▸ CA2 P00918 13/20 0.49
▸ DNASE1L3 Q13609 1/20 0.49
▸ PRMT1 Q99873 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ CA12 O43570 5/20 0.47
▸ CA14 Q9ULX7 2/20 0.47
▸ CA7 P43166 2/20 0.46
▸ ALPL P05186 1/20 0.46
▸ ALPI P09923 1/20 0.46
▸ ALPG P10696 1/20 0.46
▸ ELF3 P78545 1/20 0.44
▸ MED23 Q9ULK4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12909301 0.79 USP2 (0.68) USP2MEN1POLBKMT2AATM
SCHEMBL17903564 0.79 CA9 (0.53) USP2MEN1POLBKMT2AATM
SCHEMBL14211562 0.78 CA9 (0.44) USP2MEN1POLBKMT2AATM
SCHEMBL14527509 0.78 CA9 (0.66) USP2MEN1POLBKMT2ACA9
SCHEMBL609275 0.77 DNASE1L3 (0.65) USP2MEN1POLBKMT2AATM
SCHEMBL14932585 0.77 USP2 (0.63) USP2MEN1POLBKMT2AATM
SCHEMBL17970978 0.76 DNASE1L3 (0.64) USP2MEN1POLBKMT2AATM
SCHEMBL20059101 0.76 CA9 (0.64) USP2MEN1POLBKMT2ACA9
SCHEMBL10030600 0.76 USP2 (0.64) USP2MEN1POLBKMT2AATM
5-Iodoacetamidofluorescein SCHEMBL10146553 0.76 CA9 (0.66) USP2MEN1POLBKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150309016-A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification SIRIGEN INC. 2015-10-29 — — US disclosed
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