Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20820175 | 0.85 | PDE3A (0.53) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL19235640 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL9140896 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL9143689 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL9140892 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL18389585 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL18768286 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL20827751 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL366874 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB | |
| Gemcitabine SCHEMBL13262185 | 0.79 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10946100-B2 | Polymers including active agents | MICROVENTION, INC. (US) | 2021-03-16 | — | — | US | disclosed |
| US-20190151452-A1 | Polymers Including Active Agents | MICROVENTION, INC. | 2019-05-23 | — | — | US | disclosed |
| US-10226533-B2 | Polymer filaments including pharmaceutical agents and delivering same | MICROVENTION, INC. (US) | 2019-03-12 | — | — | US | disclosed |
| EP-3137124-B1 | POLYMERS INCLUDING ACTIVE AGENTS | MICROVENTION INC (US) | 2019-01-09 | — | — | EP | disclosed |
| WO-2015167752-A1 | POLYMERS INCLUDING ACTIVE AGENTS | MICROVENTION, INC. (US) | 2015-11-05 | — | — | WO | disclosed |
| US-20150306227-A1 | POLYMERS INCLUDING ACTIVE AGENTS | MICROVENTION, INC. | 2015-10-29 | — | — | US | disclosed |
| US-20150306227-A1 | POLYMERS INCLUDING ACTIVE AGENTS | MICROVENTION, INC. | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10226533-B2 | Polymer filaments including pharmaceutical agents and delivering same | MFAP1, ACTB, MAPT | PDE3A 2156/4885PDE4D 2220/4885SLC29A1 4062/4885 |
| US-20190151452-A1 | Polymers Including Active Agents | MFAP1, VCL, ACTB | PDE3A 3806/4885PDE4D 3708/4885SLC29A1 4481/4885 |
| US-10946100-B2 | Polymers including active agents | MFAP1, VCL, ACTB | PDE3A 3806/4885PDE4D 3708/4885SLC29A1 4481/4885 |
| US-20150306227-A1 | POLYMERS INCLUDING ACTIVE AGENTS | MFAP1, VCL, ACTB | PDE3A 3806/4885PDE4D 3708/4885SLC29A1 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.