Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MTOR | P42345 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17211614 | 0.85 | PDE3A (0.65) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL22236659 | 0.81 | PDE3A (0.49) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL12966916 | 0.79 | PDE3A (0.74) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL19187803 | 0.79 | PDE3A (0.74) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL10571048 | 0.79 | LMNA (0.56) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL8923841 | 0.78 | LMNA (0.66) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL7180 | 0.78 | LMNA (0.66) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL3141 | 0.78 | LMNA (0.66) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL20820176 | 0.78 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| Hydrochloric Acid SCHEMBL339190 | 0.77 | LMNA (0.64) | PDE3APDE4DSLC29A1LMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10231986-B2 | Amino acid phosphoramidate pronucleotides of 2′-cyano, azido and amino nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2019-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10231986-B2 | Amino acid phosphoramidate pronucleotides of 2′-cyano, azido and amino nucleosides for the treatment of HCV | PNP, RNGTT, NSUN2 | PDE3A 2273/4885PDE4D 3475/4885SLC29A1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.