Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNKSR1 | Q969H4 | 3/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17211662 | 0.85 | CNKSR1 (0.35) | CNKSR1AKT1NOS3NOS1 | |
| SCHEMBL15811497 | 0.75 | CNKSR1 (0.53) | CNKSR1AKT1 | |
| SCHEMBL17211670 | 0.72 | CNKSR1 (0.36) | CNKSR1AKT1 | |
| SCHEMBL1383804 | 0.61 | MAPT (0.46) | — | |
| SCHEMBL17211781 | 0.58 | CNKSR1 (0.42) | CNKSR1AKT1 | |
| SCHEMBL20798610 | 0.58 | CNKSR1 (0.52) | CNKSR1AKT1 | |
| SCHEMBL2412390 | 0.57 | MAPT (0.43) | — | |
| SCHEMBL20798622 | 0.57 | CNKSR1 (0.51) | CNKSR1AKT1 | |
| SCHEMBL2409633 | 0.56 | MEN1 (0.43) | — | |
| SCHEMBL20798601 | 0.56 | CNKSR1 (0.67) | CNKSR1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307482-A1 | METHODS AND COMPOSITIONS FOR INHIBITING CNKSR1 | PHUSIS THERAPEUTICS, INC. (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307482-A1 | METHODS AND COMPOSITIONS FOR INHIBITING CNKSR1 | CNKSR1, CAMKK1, CAMKK2 | CNKSR1 1/4885AKT1 936/4885NOS3 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.