Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 4/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | KDM5C | P41229 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14825504 | 0.84 | OPRD1 (0.46) | KDM4EALDH1A1OPRD1KCNH2PIK3CA | |
| SCHEMBL14825534 | 0.81 | OPRD1 (0.49) | KDM4EALDH1A1OPRD1KCNH2PIK3CA | |
| SCHEMBL14825434 | 0.75 | BCHE (0.46) | ALDH1A1 | |
| SCHEMBL14825403 | 0.75 | OPRD1 (0.58) | KDM4EALDH1A1OPRD1KCNH2PIK3CA | |
| SCHEMBL14825592 | 0.74 | BCHE (0.45) | — | |
| SCHEMBL14825424 | 0.74 | OPRD1 (0.55) | KDM4EALDH1A1OPRD1KCNH2 | |
| SCHEMBL14825842 | 0.73 | OPRD1 (0.54) | KDM4EALDH1A1OPRD1KCNH2PRMT1 | |
| SCHEMBL14825362 | 0.73 | OPRD1 (0.48) | OPRD1KCNH2PIK3CAJMJD6KDM5C | |
| SCHEMBL14825488 | 0.73 | OPRD1 (0.46) | KDM4EALDH1A1OPRD1KCNH2PIK3CA | |
| SCHEMBL14825515 | 0.72 | OPRD1 (0.51) | KDM4EALDH1A1OPRD1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578569-B1 | HETEROCYCLIC RING COMPOUND AND H1 RECEPTOR ANTAGONIST | ASKA PHARM CO LTD (JP) | 2015-10-28 | — | — | EP | disclosed |