Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4798136 | 0.85 | SLC1A3 (0.45) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2987273 | 0.85 | SLC1A3 (0.45) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2987274 | 0.85 | SLC1A3 (0.45) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6530499 | 0.83 | GRIK1 (0.39) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8020514 | 0.83 | GRIK1 (0.39) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23688391 | 0.83 | GRIK1 (0.39) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6530502 | 0.83 | GRIK1 (0.39) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8017237 | 0.83 | GRIK1 (0.39) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1133379 | 0.79 | GRIK1 (0.46) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| Urea SCHEMBL29215668 | 0.79 | SLC1A3 (0.45) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307855-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |