Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP7 | P09237 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017237 | 1.00 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1TP53 | |
| SCHEMBL6530502 | 1.00 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1TP53 | |
| SCHEMBL23688391 | 1.00 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1TP53 | |
| SCHEMBL8020514 | 1.00 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1TP53 | |
| SCHEMBL2987273 | 0.84 | SLC1A3 (0.45) | GRIK1GRIK2CYP2C19CPA1TP53 | |
| SCHEMBL4798136 | 0.84 | SLC1A3 (0.45) | GRIK1GRIK2CYP2C19CPA1TP53 | |
| SCHEMBL2987274 | 0.84 | SLC1A3 (0.45) | GRIK1GRIK2CYP2C19CPA1TP53 | |
| SCHEMBL1133379 | 0.83 | GRIK1 (0.46) | GRIK1GRIK2CYP2C19CPA1ALDH1A1 | |
| SCHEMBL17213409 | 0.83 | GRIK1 (0.37) | GRIK1GRIK2CYP2C19CPA1TP53 | |
| SCHEMBL11199369 | 0.82 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027696-B1 | COMPOSITIONS INCLUDING N-BUTYL 3-HYDROXYBUTYRATE | EASTMAN CHEM CO (US) | 2021-08-18 | — | — | EP | claimed |
| EP-3027695-B1 | AQUEOUS CLEANING COMPOSITIONS INCLUDING AN ALKYL 3-HYDROXYBUTYRATE | EASTMAN CHEM CO (US) | 2019-05-08 | — | — | EP | claimed |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2023-02-16 | — | — | US | disclosed |
| US-20210230189-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2021-07-29 | — | — | US | disclosed |
| US-20050069995-A1 | (R)-hydroxycarboxylic acid producing recombinant microorganism and process for preparing (r)-hydroxycarboxylic acid using the same | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-03-31 | — | — | US | disclosed |
| US-20030143703-A1 | Recombinant microorganism expressing polyhydroxyalkanoate biosynthesis enzyme and intracellular PHA depolymerase | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-07-31 | — | — | US | disclosed |
| WO-2003046159-A1 | (R)-HYDROXYCARBOXYLIC ACID PRODUCING RECOMBINANT MICROORGANISM AND PROCESS FOR PREPARING (R)-HYDROXYCARBOXYLIC ACID USING THE SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-05 | — | — | WO | disclosed |
| EP-0991772-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | Biocatalytics, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| US-5942644-A | Precursors for the production of chiral vicinal aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1998054350-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1998-12-03 | — | — | WO | disclosed |
| US-5834261-A | STEREOSPECIFIC REARRANGEMENT BIOSYNTHESIS BY MICROORGANISM | BIOCATALYTICS, INC. (US) | 1998-11-10 | — | — | US | disclosed |
| US-4772658-A | ADDITION POLYMERIZATION, POLYISOCYANATE-UNSATURATED ALCOHOL ADDUCT, POLYURETHANES, MOLDINGS | THE DOW CHEMICAL COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230189-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | MCL1, BCL9, BCL2L1 | GRIK1 3717/4885GRIK2 4393/4885CYP2C19 4259/4885 |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | MCL1, BCL9, BCL2L1 | GRIK1 3717/4885GRIK2 4393/4885CYP2C19 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.