Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942390 | 0.76 | CA1 (0.42) | CA1CA2CA9CA7CA12 | |
| SCHEMBL17213591 | 0.67 | — | — | |
| 1,4-Dimethoxybenzene SCHEMBL8489 | 0.64 | CA1 (1.00) | CA1CA2CA9CA7CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL21802643 | 0.64 | CA1 (1.00) | CA1CA2CA9CA7CA12 | |
| SCHEMBL4128652 | 0.64 | CA1 (0.69) | CA1CA2CA9CA7CA12 | |
| SCHEMBL2226770 | 0.64 | — | — | |
| SCHEMBL154527 | 0.64 | — | — | |
| 1,4-Dimethoxybenzene SCHEMBL5960077 | 0.62 | CA1 (0.65) | CA1CA2CA9CA7CA12 | |
| Hydrochloric Acid SCHEMBL11293911 | 0.62 | CA1 (0.65) | CA1CA2CA9CA7CA12 | |
| Water SCHEMBL9443323 | 0.62 | CA1 (0.65) | CA1CA2CA9CA7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137472-B1 | N-SUBSTITUTED PYRIDINIOPHOSPHINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2018-07-04 | — | — | EP | disclosed |
| US-9962690-B2 | N-substituted pyridiniophosphines, processes for their preparation and their use | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2018-05-08 | — | — | US | disclosed |
| US-20170050180-A1 | N-SUBSTITUTED PYRIDINIOPHOSPHINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2017-02-23 | — | — | US | disclosed |
| WO-2015165781-A1 | N-substituted pyridiniophosphines, processes for their preparation and their use | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-11-05 | — | — | WO | disclosed |
| EP-2937354-A1 | N-substituted pyridiniophosphines, processes for their preparation and their use | Studiengesellschaft Kohle mbH (DE) | 2015-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050180-A1 | N-SUBSTITUTED PYRIDINIOPHOSPHINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | PNPO, PHOSPHO1, NAPEPLD | CA1 4303/4885CA2 3424/4885CA9 3780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.