Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13553353 | 0.87 | BRD4 (0.36) | BRD4PAX8CREBBPNFKB1NFKB2 | |
| SCHEMBL16302516 | 0.85 | BRD4 (0.34) | BRD4PAX8 | |
| SCHEMBL850135 | 0.82 | BRD4 (0.33) | BRD4PAX8 | |
| SCHEMBL16302419 | 0.78 | BRD4 (0.39) | BRD4PAX8CREBBPNFKB1NFKB2 | |
| SCHEMBL851068 | 0.78 | BRD4 (0.39) | BRD4PAX8CREBBPNFKB1NFKB2 | |
| SCHEMBL13553355 | 0.78 | PAX8 (0.39) | BRD4PAX8CREBBP | |
| SCHEMBL16302542 | 0.77 | BRD4 (0.33) | BRD4PAX8 | |
| SCHEMBL879788 | 0.75 | BRD4 (0.37) | BRD4PAX8CREBBPNFKB1NFKB2 | |
| SCHEMBL13553439 | 0.74 | PTH1R (0.44) | BRD4 | |
| SCHEMBL655195 | 0.74 | BRD4 (0.43) | BRD4PAX8CREBBPNFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-B9 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2015-10-28 | — | — | EP | disclosed |