Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149668 | 1.00 | KMT2A (0.46) | KMT2AL3MBTL1KCNA3ACHENPFFR1 | |
| SCHEMBL149669 | 1.00 | KMT2A (0.46) | KMT2AL3MBTL1KCNA3ACHENPFFR1 | |
| SCHEMBL1721675 | 0.87 | KMT2A (0.46) | KMT2AL3MBTL1KCNA3ACHENPFFR1 | |
| SCHEMBL149100 | 0.87 | KMT2A (0.46) | KMT2AL3MBTL1KCNA3ACHENPFFR1 | |
| SCHEMBL149099 | 0.87 | KMT2A (0.46) | KMT2AL3MBTL1KCNA3ACHENPFFR1 | |
| SCHEMBL149953 | 0.87 | KMT2A (0.48) | KMT2AL3MBTL1KCNA3NPFFR1NPFFR2 | |
| SCHEMBL146760 | 0.86 | KMT2A (0.47) | KMT2AL3MBTL1KCNA3ACHENPFFR1 | |
| SCHEMBL459673 | 0.86 | KMT2A (0.47) | KMT2AL3MBTL1KCNA3ACHENPFFR1 | |
| SCHEMBL146759 | 0.86 | KMT2A (0.47) | KMT2AL3MBTL1KCNA3ACHENPFFR1 | |
| SCHEMBL19121559 | 0.80 | KMT2A (0.55) | KMT2AL3MBTL1KCNA3NPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406251-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103334-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |