Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146759 | 1.00 | KMT2A (0.47) | KMT2AL3MBTL1ACHECCKARCCKBR | |
| SCHEMBL146760 | 1.00 | KMT2A (0.47) | KMT2AL3MBTL1ACHECCKARCCKBR | |
| SCHEMBL149953 | 0.97 | KMT2A (0.48) | KMT2AL3MBTL1CCKARCCKBRNPFFR1 | |
| SCHEMBL149669 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1ACHECCKARCCKBR | |
| SCHEMBL1721839 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1ACHECCKARCCKBR | |
| SCHEMBL149668 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1ACHECCKARCCKBR | |
| SCHEMBL1721675 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1ACHENPFFR1NPFFR2 | |
| SCHEMBL149099 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1ACHENPFFR1NPFFR2 | |
| SCHEMBL149100 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1ACHENPFFR1NPFFR2 | |
| SCHEMBL3922813 | 0.86 | L3MBTL1 (0.44) | KMT2AL3MBTL1ACHEBCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406256-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2010103335-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |