Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725619 | 0.86 | BACE1 (0.42) | KMT2AEPHX2TLR2TLR1F10 | |
| SCHEMBL148055 | 0.86 | BACE1 (0.42) | KMT2AEPHX2TLR2TLR1F10 | |
| SCHEMBL148386 | 0.86 | BACE1 (0.42) | KMT2AEPHX2TLR2TLR1F10 | |
| SCHEMBL3805891 | 0.86 | BACE1 (0.42) | KMT2AEPHX2TLR2TLR1F10 | |
| SCHEMBL148387 | 0.86 | BACE1 (0.42) | KMT2AEPHX2TLR2TLR1F10 | |
| SCHEMBL14677261 | 0.80 | KMT2A (0.50) | KMT2AEPHX2MDM4TP53CASP3 | |
| SCHEMBL151835 | 0.80 | KMT2A (0.46) | KMT2AEPHX2MDM4TP53MDM2 | |
| SCHEMBL13186511 | 0.80 | KMT2A (0.46) | KMT2AEPHX2MDM4TP53MDM2 | |
| Hydrochloric Acid SCHEMBL145679 | 0.79 | KMT2A (0.45) | KMT2AEPHX2TLR2MDM4TP53 | |
| Hydrochloric Acid SCHEMBL145678 | 0.79 | KMT2A (0.45) | KMT2AEPHX2TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406256-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103335-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |