⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722014 | 1.00 | — | — | |
| SCHEMBL4017650 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL19590331 | 0.65 | — | — | |
| SCHEMBL20725914 | 0.65 | — | — | |
| SCHEMBL704968 | 0.64 | — | — | |
| SCHEMBL22236544 | 0.63 | — | — | |
| SCHEMBL18877169 | 0.63 | — | — | |
| SCHEMBL21063953 | 0.63 | — | — | |
| SCHEMBL117813 | 0.62 | — | — | |
| SCHEMBL1176997 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024067-B2 | Process for preparing carboxylic acid amides useful in the treatment of muscular disorders | CANBEX THERAPEUTICS LIMITED (GB) | 2015-05-05 | — | — | US | disclosed |
| EP-2403824-B1 | PROCESS FOR PREPARING CARBOXYLIC ACID AMIDES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS | UCL BUSINESS PLC (GB) | 2013-05-15 | — | — | EP | disclosed |
| US-20120101301-A1 | PROCESS FOR PREPARING CARBOXYLIC ACID AMIDES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS | UCL BUSINESS PLC (GB) | 2012-04-26 | — | — | US | disclosed |
| EP-2403824-A1 | PROCESS FOR PREPARING CARBOXYLIC ACID AMIDES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS | UCL Business Plc. (GB) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010116116-A1 | PROCESS FOR PREPARING CARBOXYLIC ACID AMIDES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS | UCL BUSINESS PLC (GB) | 2010-10-14 | — | — | WO | disclosed |